Marketing The Drum Awards

How UICC’s ‘Upside Down’ Challenge flipped global cancer awareness

By The Drum, Editorial

The Drum

November 17, 2025 | 8 min read

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The UICC’s ‘Upside Down’ Challenge won Gold in Social Purpose at The Drum Awards, leveraging a simple visual metaphor to inspire over 1,000 pieces of user-generated content, driving 6m social media engagements and amplifying a global movement for World Cancer Day.

The UICC, a global union of over a thousand cancer organisations, faced a significant challenge. They needed a single, cohesive idea for World Cancer Day that could resonate across vastly different cultures, languages, and social platforms. This idea had to achieve both broad public reach and, most importantly, high-level engagement and content creation from their own member organisations.

The primary goals were to:

  • Empower storytelling: Create a simple and accessible way for individuals impacted by cancer—patients, survivors, carers, and professionals—to share their personal stories through user-generated content.
  • Support the new campaign theme: Weave in UICC’s new three-year theme, 'United by Unique,' which emphasises a people-centred approach. The campaign needed to show how individual UGC, when shared together, could form a powerful, united movement.
  • Increase engagement through UGC: Drive a measurable increase in user-generated content on social media compared to previous years.
  • Engage partners: Provide UICC's vast network with a simple, scalable activation they could adopt and amplify to encourage their own communities to participate.

Our strategy was built on a simple, yet profoundly human insight: a cancer diagnosis turns a person’s world upside down. This was the emotional truth that underpinned our creative concept. We translated this insight into a bold and inclusive visual metaphor: the 'Upside Down' Challenge. The campaign invited people to literally flip a photo or video of themselves on social media and share their personal story. This act was designed to be universally understood. The visual of a flipped image immediately grabbed attention in a crowded feed, prompting a moment of pause and curiosity. It was a visual cue that broke through language and cultural barriers, making it instantly recognisable and shareable globally. The success of this approach relied on the active participation of both member organisations and high-profile influencers who would initially post upside-down photos with no context, building curiosity and intrigue before revealing the reason on World Cancer Day.

Execution

The true creative excellence of the 'Upside Down' Challenge was its simplicity and accessibility for content creators. It required no expensive technology—all that was needed was a mobile phone with a camera and a story.

The visual device of a flipped photo or video was a bold, eye-catching disruption to the typical social media feed. This visual acted as a powerful invitation, allowing individuals to share their stories in a way that felt natural, whether through a written message, a video monologue, or a simple image. The core concept was designed to accommodate the full spectrum of emotions associated with cancer. The use of a unified visual...the flipped photo, which seamlessly linked every unique story, turning a collection of individual experiences into a cohesive, global narrative.

A cornerstone of our implementation was the strategic engagement of UICC’s vast network of member organisations, which served as the primary engine for driving UGC. To facilitate this, we created a comprehensive campaign toolkit that was distributed to over 1,250 member organisations. This toolkit was instrumental, providing everything from pre-made assets and logos to social media copy and best practices for influencer engagement. Key partners like Fujifilm, Roche, and Jazz Pharma used these tools to activate the campaign on their own channels, successfully encouraging their own communities to create and share content, which amplified the message far beyond our direct reach.

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Another crucial part of the campaign's launch and in mobilising more users to engage in the campaign was our dedicated influencer engagement programme. Our team reached out to high-profile influencers with a voice and platform to help further mobilise our online community beyond earned channels. @KingOfChemo, with his 6.8 million followers, was one of over ten key high-profile influencers that the team engaged to participate and share the campaign.

The campaign was rolled out across all major social media channels, including Instagram, TikTok, X, LinkedIn, and Facebook. We provided participants with clear and concise instructions: 1) take or choose a picture/video, 2) flip it upside down, 3) post it with your story, and 4) use the designated hashtags #WorldUpsideDown and #UnitedByUnique.

Though not part of the initial brief, we secured a pro-bono partnership with Ocean Outdoor to further amplify the campaign. By displaying key campaign messages on prominent digital screens in high-traffic UK locations, we drove audiences online and encouraged real-world participation, ultimately leading to more user-generated content.

Results

The 'Upside Down' Challenge was a resounding success, proving the power of a creative social media idea to inspire action and create a global movement through UGC. The campaign achieved and exceeded UICC’s objective of engaging more partners and users and generating more UGC than the previous year.

Community Involvement: The 'Upside Down' Challenge was the most successful social media campaign that the UICC has run for a World Cancer Day, measured by the amount of UGC shared. It inspired over 1,000 pieces of user-generated content from individuals around the world. This content was the primary driver of the campaign's incredible reach and engagement.

The audience-led content contributed to the overall total engagement for World Cancer Day, a 6,000,000 engagements on social media. The campaign's message was met with overwhelmingly positive sentiment, with 92% of messages carrying a positive emotional tone.

Where we don’t know how OOH directly impacted the campaign. With no media budget, our pro-bono partnership with Ocean Outdoor secured 1,529,413 additional impressions on World Cancer Day in key UK cities. This success was a direct result of Hey Honey's commitment to the cause, generating an additional (and free) for the campaign.

The 'Upside Down' Challenge was designed as the first phase of a three-year campaign. The user-generated stories collected in 2025 are now used as powerful advocacy tools. Featured on UICC’s website, they serve as a body of evidence to influence policymakers, healthcare leaders, and systems to adopt a more people-centred approach to care. UGC was not a one-off asset, but a fundamental building block for a long-term strategy to drive real, systemic change.

The campaign’s success was rooted in its creative ingenuity and universal accessibility, allowing a diverse global audience to participate in a shared narrative. This approach demonstrated that a simple, human-centric idea can transcend organisational silos and cultural divides, creating a united voice for a cause that affects us all. The UGC model enabled the campaign to scale, powered by the voices of the community.

Ready to get your work recognized on a global stage? Enter The Drum Awards today. Need more inspiration? Read our Award Winning Case Studies.

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Hey Honey, we're a global social-first creative agency built for the future, putting culture, community, and the planet first. From our headquarters in Amsterdam,...

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